Since membrane-bound macromolecules provide the most general and powerful mechanisms for biological ion sensing and ion channelling, a new type of polymer-modified electrode was designed: a multiphase material consisting of poly(styrene-co-acrylonitrile) and poly(L-glutamate) was synthesized as the block copolymer. The material has enabled polypeptides to be immobilized onto electrodes just by dipping. Electrochemical responses towards Ca 2 ? were obtained based on the permeability change of the redox-active species as the indicator. The modified electrode has remarkable stability due to the vinyl polymer chains which serve as building blocks of the membrane.
Посилання на статтю:
Multiphase material containing poly(L-glutamate) for biomembrane mimetic sensors* / Koji Nakano, Yuji Fujita, Mizuo Maedat and Makoto Takagi // Polymer. – 1992. – Vol 33. – P. 3997-4000.