The possibility of preparing polyester and poly(ether-ester) networks from R,S-malic acid and diols or poly(ether alcohol)s by polycondensation was investigated. The reactions were carried out in tetrahydrofuran in the presence of N,N'-dicyclohexylcarbodiimide and p-toluenesulfonic acid and pyridine as catalyst. I.r., tH n.m.r, and mass spectra of the crosslinked products obtained, confirmed their ester and ether-ester structure. The dependence of swelling and some thermodynamic parameters upon the kind of alcohol used was established. The new synthesized crosslinked polymers, which can be swelled in a variety of solvents and are thermohydrolytically unstable, can be used as biodegradable carriers for drugs and microelements
Посилання на статтю:
Poly(ether-ester) networks prepared by polycondensation of R,S-malic acid with diols and polyether alcohols in the presence of N,N'-dicyclohexylcarbodiimide / Nadya Belcheva*, Todor Zlatkov, Ivan M. Panayotov and ChristoTsvetanov // Polymer. – 1993. – Vol 34. – P. 2213-2217.